GLP-1 Receptor Agonists
MetabolicThe class of incretin-mimicking peptides that reshaped the landscape of metabolic medicine — and generated one of the most significant regulatory debates in modern pharmacy.
Read guideEducational Resource
Peptides occupy a contested space in modern medicine — some are FDA-approved pharmaceuticals with completed Phase 3 trials; others are research compounds studied almost exclusively in animals. This hub maps the research and regulatory landscape for eight of the most discussed peptides in clinician-supervised contexts. Each guide covers mechanism of action, what has actually been studied and in what populations, current regulatory status in the United States, and relevant considerations for anyone discussing these compounds with a licensed clinician. Nothing here constitutes medical advice or a recommendation to use any specific compound.
Incretin-based and metabolic signaling peptides
The class of incretin-mimicking peptides that reshaped the landscape of metabolic medicine — and generated one of the most significant regulatory debates in modern pharmacy.
Read guideTissue repair, wound healing, and anti-inflammatory research
A synthetic pentadecapeptide derived from a gastric protein sequence, studied extensively in animal models for tissue repair — and removed from the FDA's 503A compounding list in late 2023.
Read guideA synthetic fragment of the naturally occurring protein thymosin beta-4, studied in preclinical models for its roles in tissue repair, angiogenesis, and anti-inflammatory signaling.
Read guideGHRH analogs and GH secretagogues
A selective growth hormone secretagogue of the GHRP class that stimulates pulsatile GH release from pituitary somatotrophs with a specificity profile distinct from other peptides in its family.
Read guideA long-acting synthetic GHRH analog engineered to bind albumin in the bloodstream, dramatically extending its half-life and producing sustained elevations in growth hormone and IGF-1 compared to native GHRH.
Read guideTelomere, epigenetic, and aging-biology research
A naturally occurring copper-binding tripeptide with a fifty-year research history spanning wound healing, skin remodeling, and gene expression — used widely in cosmetics and studied for systemic regenerative applications.
Read guideA tetrapeptide synthesized from the amino acid composition of a bovine pineal extract, studied primarily by Russian researchers for telomerase activation and putative longevity effects — with an evidence base that is genuinely intriguing but substantially weaker than most agents in this guide.
Read guideFDA-approved peptides and cross-category compounds
The only peptide in this guide with FDA approval for a human indication — bremelanotide (Vyleesi) was approved in 2019 for premenopausal women with acquired, generalized hypoactive sexual desire disorder.
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